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Because gastrointestinal effects are dose-related, gradual titration helps improve tolerability

Glycine is essential for building collagen, which supports healthy skin, joints, and connective tissues

Toxicol Appl Pharmacol 195:6272 Pastoris O, Dossena M, Vercesi L, Bruseghini M, Pagnin A, Ceriana P (1991) Biochemical changes induced in the myocardial cell during cardioplegic arrest supplemented with creatine phosphate